Biology : PU-CET (U.G) 2018 Panjab University Entrance Exam With Answers

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7.

If A Mutation In DNA Leads To Change In Codon UUU To UUC In a mRNA, The Mutation Would Be A

A: Mis-sense Mutation
B: Silent Mutation
C: Non-sense Mutation
D: Frame-Shift Mutation

The answer is: B

Explanation

The genetic code is composed of sets of three nucleotides called codons, which specify the amino acids that make up a protein. Some amino acids are specified by multiple codons. For example, the amino acid phenylalanine can be specified by the codons UUU or UUC.

If a mutation in DNA leads to a change in the codon UUU to UUC in mRNA, the mutation would be a silent mutation.

A silent mutation is a type of point mutation in which a change in the nucleotide sequence of DNA does not result in a change in the amino acid sequence of the protein. This is because the codon UUC also codes for phenylalanine, which is the same amino acid specified by the original codon UUU.

Therefore, the correct answer is B: Silent Mutation. A mutation from UUU to UUC would not result in a change in the amino acid sequence of the protein, and thus it is considered a silent mutation.