The procedure for selecting hybridoma cells requires HAT medium containing aminopterin. This is included in the medium because;

Biotechnology Engineering (M.Phil./Ph.D.) 2019 Panjab University Entrance Exam With Answers

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25.

A: It provides a precursor for purine metabolism.

B: It inhibits purinre metabolism activity.

C: It provides a precursor for dihydrofolate reductase activity.

D: It inhibits dihydrofolate reductase activity.

The answer is: D

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