Bio-Physics (M.Phil./Ph.D.) 2019 Panjab University Entrance Exam With Answers

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1. The most significant drawback in electron microscope is that

2. Mycobacterium tuberculosis is an intra-cellular bacterium. It prefers to infect

3. What does θ signifies in Brags equation: 2d Sin θ=nλ

4. Which gene transfer technique involves the use of a fatty bubble to carry a gene into a somatic cell?

5. What reagent is quantified when performing an indirect ELISA?

6. The vector for T -DNA is:

7. Asprin, used as a common analgesic, antipyretic and anti-inflammatory agent, inhibits the synthesis of which one of the following ?

8. The S wave form of normal human ECG originates due to:

9. Which one of the methods listed below is the most sensitive label free quantification methods for proteins?

10. Which of the following proteins acts as an energy transducer?

11. Which of the following is unfavorable for protein folding?

12. Recombinant proteins are

13. Immunoprecipitation involve the purification of

14. Bouguer’s law relates

15. Which among the following is the simplest method to estimate the concentration of glycerol in an aqueous solution of glycerol ?

16. Choose the correct statement about peptides in Ramachandran plot.

17. An optical measurement of protein is taken both before and after digestion of the protein by a protease. In which of the following spectroscopic measurement the signal change, i.e., before v/s after protease treatment, could be the maximum?

18. The presence and distribution of specific mRNAs within a cell can be detected by

19. Which one of the following analytical techniques does NOT involve an optical measurement?

20. The secondary antibodies routinely used for the detection of primary antibodies in western blotting experiment are

21. Histone deacytalase (HDAC) catalyses the removal of acetyl group from N-terminal of histones. Which amino acid of histone is involved in this process?

22. Where are CD-45 cells responsible for signal transduction in the body located?

23. Which of the following antibiotics work by inhibiting protein synthesis in the target organism?

24. Which one of the following chemicals is a DNA intercalator?

25. The appropriate match in Column 1 and 2 is

26. Which of the following groups contain only aromatic Aminoacids?

27. Immediate hypersentivity reactions are associated with?

28. The Biological role of Cytochrome P-450 is

29. If half-life of 100 g iodine (I131) is 8 days, how many grams will remain in 32 days

30. Which of the following statements is/are correct?

31. A neoplasm is

32. “A single ring-shaped DNA molecule” is a description of

33. The tumor suppressor gene that shows up in approximately half of all U.S. cancers is called

34. Increased blood flow to a cancerous tumor is called

35. A mutation that removes a base pair and thus offsets the reading frame of the genetic sequence by one letter is called

36. Lack of thymus leads to increased infection in humans such a condition called

37. The proofreading of newly synthesized DNA, to excise incorrect nucleotides which have been inserted, is done by :

38. The codon is found in :

39. The size of the E.coli genome is

40. An enzyme that recognizes a specific (palindromic) sequence and cuts within a DNA molecule is called a(n):

41. Which polymerase made widespread use of PCR possible:

42. G-proteins are involved in relying signals through G-protein linked receptors. Which of the following forms of G-proteins considered in to be active state?

43. Which one of the following compounds does not act as second messenger during signaling process?

44. Which of the following biochemical reactions is most commonly utilized by living cells to propagate intracellular signals?

45. Tight junctions:

46. Which of the following is the component in the signaling pathway stimulated by receptor tyrosine kinases?

47. Which of the following wavelength ranges is associated with UV spectroscopy?

48. Electron microscopes have higher resolution than any type of light microscope because of their:

49. Lycopene (λmax = 469 nm) is present in tomatoes. What colour of light does lycopene absorb?

50. Which of the following is not a limitation of Beer Lambert’s law, which gives the relation between absorption, thickness, and concentration?