7.
LDL binds with cell surface receptor and gets internalized via clathrin-mediated endocytosis. This process helps in maintaining the cholesterol-LDL level in the plasma. However, in a disease known as familial hypercholesterolemia (FH), very high levels of plasma cholesterol is found. This could be due to mutation in which one of the following genes in FH patients?
A:
Clathrin
B:
LDL
C:
LDL receptor
D:
Adaptor
The answer is:
C
