Biology : PU-CET (U.G) 2016 Panjab University Entrance Exam With Answers

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9.

The Chromosome Analysis Of A Newly Born Male Revealed That Non-Disjunction Of Sex Chromosomes at Mitosis Has Occurred Once. The Most Likely Sex Chromosome Composition Of The Individual Is :

A: XY
B: XO
C: XXY
D: XYY

The answer is: C

Explanation

The most likely sex chromosome composition of the individual with non-disjunction of sex chromosomes at mitosis is XXY, which is also known as Klinefelter syndrome.

Non-disjunction is an error that can occur during cell division, where chromosomes fail to separate properly. In the case of a male individual, non-disjunction of sex chromosomes at mitosis can lead to the formation of sperm cells with an extra X chromosome, resulting in an XXY karyotype.

Option A (XY) is the normal male karyotype, and non-disjunction of sex chromosomes at mitosis would not result in this karyotype.

Option B (XO) is the karyotype of individuals with Turner syndrome, which is caused by the absence of an X chromosome in females.

Option D (XYY) is the karyotype of individuals with Jacob syndrome, which is a rare chromosomal disorder. However, non-disjunction of sex chromosomes at mitosis would not result in this karyotype.

Therefore, the most likely sex chromosome composition of the individual with non-disjunction of sex chromosomes at mitosis is XXY (Option C).