Bio-Chemistry (M.Phil./Ph.D.) 2014 Panjab University Entrance Exam With Answers

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23.

Which statement best describes the main distinction between the origin of the two classes of small regulatory RNAs: siRNA and miRNA ?

A: siRNAs originate within the cell cytoplasm; miRNAs originate from the cell genome
B: siRNAs originate from predominantly exogenous dsRNA; miRNAs originate from the cell genome
C: miRNAs are expressed whenever siRNAs are unable to appropriately degrade RNA sequences
D: miRNAs are processed from dsRNA viruses, siRNAs are processed from ssRNA viruses

The answer is: B