A major advance in the application of mass spectrometry to macromolecule came with the development of techniques to overcome which One of the following problems:

Bio-Chemistry (M.Phil./Ph.D.) 2019 Panjab University Entrance Exam With Answers

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A: Macromolecules were insoluble in solvents used in mass spectrometry

B: Mass spectrometric analyses were too complex

C: Mass spectrometric analysis involved molecules in gas phase

D: Most macromolecules could not be purified to the degree needed for this technique

The answer is: C

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