Bio-Physics (M.Phil./Ph.D.) 2015 Panjab University Entrance Exam With Answers

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42.

The erd-9 gene appears to be a binary switch that regulates cellular survival and apoptosis in nematodes considering that Ced-9 proteins can bind to and inactivate Ced-4, which of the following would lead to apoptosis-

A: activation of Ced -9 gene
B: Loss of function of Ced-9 gene
C: Loss of function of Ced-3 gene
D: Loss of function of Ced-4 gene

The answer is: C