Bio-Physics (M.Phil./Ph.D.) 2016 Panjab University Entrance Exam With Answers

Practice Mode:
44.

Restriction fragment Length-polymorphism (RFLP) can only be used to follow the inheritance of a genetic disease if:

A: The disease causing mutation is at or closely linked to an altered restriction site
B: Proteins of mutated and normal genes migrate differently upon gel electrophoresis
C: Mutations are outside of restriction sites so that the cleaving still occurs
D: Restriction fragments remain the same size but their charge changes

The answer is: A