Explanation
In human beings, the 45-chromosomes/single X/O (XO) abnormality causes Turner's syndrome.
Turner's syndrome is a genetic disorder that affects females and is caused by the complete or partial absence of one of the two X chromosomes. Instead of the typical XX chromosome complement, individuals with Turner's syndrome have a single X chromosome (XO). This can result in a range of physical and developmental abnormalities, including short stature, infertility, heart defects, and learning difficulties.
Therefore, option C (Turner's Syndrome) is the correct answer.
Option A (Down's Syndrome) is caused by the presence of an extra copy of chromosome 21,
while option B (Klinefelter's Syndrome) is caused by the presence of an extra X chromosome in males (XXY).
Option D (Edward's Syndrome) is caused by the presence of an extra copy of chromosome 18.